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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPZ
All Species:
22.73
Human Site:
S243
Identified Species:
55.56
UniProt:
P25189
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25189
NP_000521.1
248
27555
S243
K
A
K
G
L
G
E
S
R
K
D
K
K
_
_
Chimpanzee
Pan troglodytes
XP_001173975
258
28498
S253
K
A
K
G
L
G
E
S
R
K
D
K
K
_
_
Rhesus Macaque
Macaca mulatta
XP_001118030
256
28332
S251
K
A
K
G
L
G
E
S
R
K
D
K
K
_
_
Dog
Lupus familis
XP_545771
258
28504
S253
K
S
K
G
L
G
E
S
R
K
D
K
K
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P27573
248
27603
S243
K
S
K
G
L
G
E
S
R
K
D
K
K
_
_
Rat
Rattus norvegicus
P06907
248
27552
S243
K
S
K
G
L
G
E
S
R
K
D
K
K
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513720
278
30639
N262
H
S
G
G
Q
H
S
N
K
I
N
K
S
E
S
Chicken
Gallus gallus
P37301
249
27448
E243
K
S
K
G
A
P
G
E
A
R
K
D
K
K
_
Frog
Xenopus laevis
A2VD98
245
27230
Zebra Danio
Brachydanio rerio
NP_919342
203
22079
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
95.6
91.8
N.A.
93.5
93.9
N.A.
28
73
61.6
41.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.1
96
94.1
N.A.
97.1
96.7
N.A.
44.2
83.5
77.8
59.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
92.3
N.A.
92.3
92.3
N.A.
13.3
28.5
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
42.8
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
0
10
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
60
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
60
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
80
0
60
10
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
70
0
70
0
0
0
0
0
10
60
10
70
70
10
0
% K
% Leu:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
60
10
0
0
0
0
0
% R
% Ser:
0
50
0
0
0
0
10
60
0
0
0
0
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
70
% _